Search on: BONE MORPHOGENETIC PROTEINS 
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Descriptor English:   Bone Morphogenetic Proteins 
Descriptor Spanish:   Proteínas Morfogenéticas Óseas 
Descriptor Portuguese:   Proteínas Morfogenéticas Ósseas 
Tree Number:   D12.644.276.954.200
D12.776.467.942.200
D23.529.942.200
Definition English:   Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. 
Indexing Annotation English:   general; prefer specifics
History Note English:   97; was BONE MORPHOGENETIC PROTEIN (NM) 1981-96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   33041 
Unique Identifier:   D019485 

Occurrence in VHL:
 

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